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Title   유방암 500예의 임상적 고찰 ( A Clinical Study of 500 Cases Breast Cancer )
Publicationinfo   1997 Jan; 029(06): 1061-1069.
Key_word   Breast cancer, Clinical characteristics, Survival rates
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Abstract   Purpose: We investigated the clinical characteristics of breast cancers and its significance. Material and method: We evaluated the clinical characteristics of 500 women with breast cancer who were diagnosed and treated by one surgeon between March 1991 and August 1996. Results: The median age was 46.7 years and the most common age group was 40's. The presenting symptoms for most patients were palpable mass(75.2%) followed by abnormal mammographic findings(8.4%), pain(6.3%) and nipple discharges(4.7%), and the duration of symptoms was less than 1 month in 41.4%. Fifty three percent of the 500 cases had T lesion(size; 2 to 5 cm). With the increase of tumor size, overall and disease free survival rates(OS, DFS) were decreased. Surgical treatment consisted of modified radical mastectomy(52.8%) and partial mastectomy(33.6%) The most common stage was II(42.3%) and the early breast cancer(stage 0, I, II) was 388cases(78.1%) and the stage were inversely correlated with DFS and OS. The positivity of axillary lymph node was 39.3% and the number of the metastatic lymph nodes was inversely correlated with DFS and OS. The pathologic types were infiltrating ductal carcinoma(83.0%), ductal carcinoma in situ(12.8%), infiltrating lobular carcinoma(1.2%), lobular carcinoma in situ(0.4%) and Pagets disease(2.0%). ER positivity was 48.9% and PR 46.9%. ER positive patients showed survival benefit compared to ER negative patients. The common sites of distant metastases were lung, bone and liver. Conlcusions: Our patients with breast cancer were younger than those of western and showed the impacts on survival according to the lymph node status,tumor size.
저 자   박인식(In Sik Park),구자윤(Ja Yun Koo),이희대(Hy Do Lee),정우희(Woo Hee Jung)